| | Civilian Labor Force, 2021 | Persons Employed, 2021 | Persons Unemployed, 2021 | Unemployment Rate, 2021 | Unemployment Rate, Percent of U.S. Average, 2021 |
|
| United States | 161,204,000 | 152,581,000 | 8,623,000 | 5.3% | 100.0% |
| Appalachian Region | 12,010,661 | 11,455,917 | 554,744 | 4.6% | 86.3% |
| Kentucky | 2,010,884 | 1,921,355 | 89,529 | 4.5% | 83.2% |
| Appalachian Kentucky | 422,354 | 400,009 | 22,345 | 5.3% | 98.9% |
|
| County |
| Adair | 7,172 | 6,831 | 341 | 4.8% | 88.9% |
| Bath | 4,592 | 4,341 | 251 | 5.5% | 102.2% |
| Bell | 8,084 | 7,641 | 443 | 5.5% | 102.4% |
| Boyd | 16,989 | 15,989 | 1,000 | 5.9% | 110.0% |
| Breathitt | 3,207 | 2,947 | 260 | 8.1% | 151.6% |
| Carter | 9,506 | 8,812 | 694 | 7.3% | 136.5% |
| Casey | 6,686 | 6,421 | 265 | 4.0% | 74.1% |
| Clark | 16,881 | 16,171 | 710 | 4.2% | 78.6% |
| Clay | 5,108 | 4,780 | 328 | 6.4% | 120.0% |
| Clinton | 3,908 | 3,740 | 168 | 4.3% | 80.4% |
| Cumberland | 3,263 | 3,152 | 111 | 3.4% | 63.6% |
| Edmonson | 4,601 | 4,374 | 227 | 4.9% | 92.2% |
| Elliott | 1,861 | 1,714 | 147 | 7.9% | 147.7% |
| Estill | 5,049 | 4,800 | 249 | 4.9% | 92.2% |
| Fleming | 6,007 | 5,726 | 281 | 4.7% | 87.5% |
| Floyd | 10,664 | 9,956 | 708 | 6.6% | 124.1% |
| Garrard | 7,539 | 7,216 | 323 | 4.3% | 80.1% |
| Green | 5,097 | 4,915 | 182 | 3.6% | 66.8% |
| Greenup | 12,803 | 11,965 | 838 | 6.5% | 122.4% |
| Harlan | 6,367 | 5,860 | 507 | 8.0% | 148.9% |
| Hart | 7,586 | 7,267 | 319 | 4.2% | 78.6% |
| Jackson | 4,029 | 3,788 | 241 | 6.0% | 111.8% |
| Johnson | 6,548 | 6,097 | 451 | 6.9% | 128.8% |
| Knott | 4,229 | 3,944 | 285 | 6.7% | 126.0% |
| Knox | 9,827 | 9,245 | 582 | 5.9% | 110.7% |
| Laurel | 24,718 | 23,644 | 1,074 | 4.3% | 81.2% |
| Lawrence | 5,286 | 4,962 | 324 | 6.1% | 114.6% |
| Lee | 2,001 | 1,894 | 107 | 5.3% | 100.0% |
| Leslie | 2,502 | 2,314 | 188 | 7.5% | 140.5% |
| Letcher | 5,959 | 5,535 | 424 | 7.1% | 133.0% |
| Lewis | 4,609 | 4,276 | 333 | 7.2% | 135.1% |
| Lincoln | 9,166 | 8,679 | 487 | 5.3% | 99.3% |
| Madison | 45,866 | 44,054 | 1,812 | 4.0% | 73.9% |
| Magoffin | 3,168 | 2,800 | 368 | 11.6% | 217.2% |
| Martin | 2,314 | 2,114 | 200 | 8.6% | 161.6% |
| McCreary | 4,782 | 4,519 | 263 | 5.5% | 102.8% |
| Menifee | 2,289 | 2,140 | 149 | 6.5% | 121.7% |
| Metcalfe | 3,911 | 3,710 | 201 | 5.1% | 96.1% |
| Monroe | 4,590 | 4,416 | 174 | 3.8% | 70.9% |
| Montgomery | 11,452 | 10,877 | 575 | 5.0% | 93.9% |
| Morgan | 4,238 | 4,007 | 231 | 5.5% | 101.9% |
| Nicholas | 3,279 | 3,145 | 134 | 4.1% | 76.4% |
| Owsley | 1,048 | 977 | 71 | 6.8% | 126.7% |
| Perry | 7,915 | 7,449 | 466 | 5.9% | 110.1% |
| Pike | 18,860 | 17,726 | 1,134 | 6.0% | 112.4% |
| Powell | 5,072 | 4,839 | 233 | 4.6% | 85.9% |
| Pulaski | 25,492 | 24,291 | 1,201 | 4.7% | 88.1% |
| Robertson | 794 | 762 | 32 | 4.0% | 75.3% |
| Rockcastle | 6,345 | 6,042 | 303 | 4.8% | 89.3% |
| Rowan | 9,886 | 9,392 | 494 | 5.0% | 93.4% |
| Russell | 6,041 | 5,725 | 316 | 5.2% | 97.8% |
| Wayne | 7,263 | 6,908 | 355 | 4.9% | 91.4% |
| Whitley | 13,709 | 13,049 | 660 | 4.8% | 90.0% |
| Wolfe | 2,196 | 2,071 | 125 | 5.7% | 106.4% |
