| | Population Estimates Base, April 1, 2000 | Population Estimate, July 1, 2009 | Numeric Population Change, April 1, 2000 to July 1, 2009 | Percent Population Change, April 1, 2000 to July 1, 2009 |
|
| United States | 281,424,602 | 307,006,550 | 25,581,948 | 9.1% |
| Appalachian Region | 23,642,949 | 24,993,391 | 1,350,442 | 5.7% |
| Kentucky | 4,042,288 | 4,314,113 | 271,825 | 6.7% |
| Appalachian Kentucky | 1,160,654 | 1,194,500 | 33,846 | 2.9% |
|
| County |
| Adair | 17,244 | 18,029 | 785 | 4.6% |
| Bath | 11,094 | 11,618 | 524 | 4.7% |
| Bell | 30,060 | 28,972 | -1,088 | -3.6% |
| Boyd | 49,752 | 48,527 | -1,225 | -2.5% |
| Breathitt | 16,100 | 15,575 | -525 | -3.3% |
| Carter | 26,880 | 26,771 | -109 | -0.4% |
| Casey | 15,447 | 16,498 | 1,051 | 6.8% |
| Clark | 33,144 | 36,159 | 3,015 | 9.1% |
| Clay | 24,556 | 23,629 | -927 | -3.8% |
| Clinton | 9,634 | 9,403 | -231 | -2.4% |
| Cumberland | 7,147 | 6,706 | -441 | -6.2% |
| Edmonson | 11,646 | 11,926 | 280 | 2.4% |
| Elliott | 6,756 | 9,083 | 2,327 | 34.4% |
| Estill | 15,307 | 14,859 | -448 | -2.9% |
| Fleming | 13,792 | 14,667 | 875 | 6.3% |
| Floyd | 42,443 | 41,899 | -544 | -1.3% |
| Garrard | 14,792 | 17,085 | 2,293 | 15.5% |
| Green | 11,515 | 11,510 | -5 | 0.0% |
| Greenup | 36,888 | 38,020 | 1,132 | 3.1% |
| Harlan | 33,202 | 30,956 | -2,246 | -6.8% |
| Hart | 17,445 | 18,396 | 951 | 5.5% |
| Jackson | 13,495 | 13,243 | -252 | -1.9% |
| Johnson | 23,446 | 23,827 | 381 | 1.6% |
| Knott | 17,649 | 17,126 | -523 | -3.0% |
| Knox | 31,783 | 32,710 | 927 | 2.9% |
| Laurel | 52,715 | 57,749 | 5,034 | 9.5% |
| Lawrence | 15,569 | 16,573 | 1,004 | 6.4% |
| Lee | 7,916 | 7,339 | -577 | -7.3% |
| Leslie | 12,401 | 11,503 | -898 | -7.2% |
| Letcher | 25,277 | 23,633 | -1,644 | -6.5% |
| Lewis | 14,092 | 13,752 | -340 | -2.4% |
| Lincoln | 23,361 | 25,172 | 1,811 | 7.8% |
| Madison | 70,872 | 83,258 | 12,386 | 17.5% |
| Magoffin | 13,332 | 13,166 | -166 | -1.2% |
| Martin | 12,578 | 13,070 | 492 | 3.9% |
| McCreary | 17,080 | 17,795 | 715 | 4.2% |
| Menifee | 6,556 | 6,593 | 37 | 0.6% |
| Metcalfe | 10,037 | 10,063 | 26 | 0.3% |
| Monroe | 11,756 | 11,569 | -187 | -1.6% |
| Montgomery | 22,554 | 25,835 | 3,281 | 14.5% |
| Morgan | 13,948 | 14,092 | 144 | 1.0% |
| Nicholas | 6,813 | 6,874 | 61 | 0.9% |
| Owsley | 4,858 | 4,619 | -239 | -4.9% |
| Perry | 29,422 | 29,136 | -286 | -1.0% |
| Pike | 68,734 | 65,446 | -3,288 | -4.8% |
| Powell | 13,237 | 13,566 | 329 | 2.5% |
| Pulaski | 56,217 | 60,853 | 4,636 | 8.2% |
| Robertson | 2,263 | 2,237 | -26 | -1.1% |
| Rockcastle | 16,582 | 16,504 | -78 | -0.5% |
| Rowan | 22,094 | 22,872 | 778 | 3.5% |
| Russell | 16,315 | 17,377 | 1,062 | 6.5% |
| Wayne | 19,923 | 20,748 | 825 | 4.1% |
| Whitley | 35,870 | 38,813 | 2,943 | 8.2% |
| Wolfe | 7,065 | 7,099 | 34 | 0.5% |
