| | Civilian Labor Force, 2022 | Persons Employed, 2022 | Persons Unemployed, 2022 | Unemployment Rate, 2022 | Unemployment Rate, Percent of U.S. Average, 2022 |
|
| United States | 164,287,000 | 158,291,000 | 5,996,000 | 3.6% | 100.0% |
| Appalachian Region | 12,135,996 | 11,700,293 | 435,703 | 3.6% | 98.4% |
| Mississippi | 1,248,093 | 1,200,234 | 47,859 | 3.8% | 105.1% |
| Appalachian Mississippi | 266,450 | 256,444 | 10,006 | 3.8% | 102.9% |
|
| County |
| Alcorn | 14,959 | 14,430 | 529 | 3.5% | 96.9% |
| Benton | 3,046 | 2,900 | 146 | 4.8% | 131.3% |
| Calhoun | 5,374 | 5,157 | 217 | 4.0% | 110.6% |
| Chickasaw | 6,561 | 6,270 | 291 | 4.4% | 121.5% |
| Choctaw | 3,569 | 3,441 | 128 | 3.6% | 98.3% |
| Clay | 8,670 | 8,322 | 348 | 4.0% | 110.0% |
| Itawamba | 10,208 | 9,867 | 341 | 3.3% | 91.5% |
| Kemper | 3,236 | 3,049 | 187 | 5.8% | 158.3% |
| Lee | 40,555 | 39,233 | 1,322 | 3.3% | 89.3% |
| Lowndes | 24,478 | 23,494 | 984 | 4.0% | 110.1% |
| Marshall | 14,201 | 13,638 | 563 | 4.0% | 108.6% |
| Monroe | 15,487 | 14,884 | 603 | 3.9% | 106.7% |
| Montgomery | 3,893 | 3,731 | 162 | 4.2% | 114.0% |
| Noxubee | 3,386 | 3,189 | 197 | 5.8% | 159.4% |
| Oktibbeha | 22,056 | 21,176 | 880 | 4.0% | 109.3% |
| Panola | 12,276 | 11,715 | 561 | 4.6% | 125.2% |
| Pontotoc | 14,816 | 14,316 | 500 | 3.4% | 92.5% |
| Prentiss | 11,206 | 10,840 | 366 | 3.3% | 89.5% |
| Tippah | 9,727 | 9,404 | 323 | 3.3% | 91.0% |
| Tishomingo | 8,417 | 8,115 | 302 | 3.6% | 98.3% |
| Union | 14,554 | 14,136 | 418 | 2.9% | 78.7% |
| Webster | 3,873 | 3,726 | 147 | 3.8% | 104.0% |
| Winston | 7,135 | 6,832 | 303 | 4.2% | 116.4% |
| Yalobusha | 4,767 | 4,579 | 188 | 3.9% | 108.1% |
