| | Civilian Labor Force, 2020 | Persons Employed, 2020 | Persons Unemployed, 2020 | Unemployment Rate, 2020 | Unemployment Rate, Percent of U.S. Average, 2020 |
|
| United States | 160,742,000 | 147,795,000 | 12,947,000 | 8.1% | 100.0% |
| Appalachian Region | 12,035,782 | 11,141,797 | 893,985 | 7.4% | 92.2% |
| Mississippi | 1,243,515 | 1,145,211 | 98,304 | 7.9% | 98.1% |
| Appalachian Mississippi | 265,369 | 244,445 | 20,924 | 7.9% | 97.9% |
|
| County |
| Alcorn | 15,117 | 14,189 | 928 | 6.1% | 76.2% |
| Benton | 2,991 | 2,748 | 243 | 8.1% | 100.9% |
| Calhoun | 5,514 | 5,077 | 437 | 7.9% | 98.4% |
| Chickasaw | 6,867 | 6,140 | 727 | 10.6% | 131.4% |
| Choctaw | 3,545 | 3,324 | 221 | 6.2% | 77.4% |
| Clay | 7,817 | 6,925 | 892 | 11.4% | 141.7% |
| Itawamba | 10,154 | 9,461 | 693 | 6.8% | 84.7% |
| Kemper | 3,311 | 3,000 | 311 | 9.4% | 116.6% |
| Lee | 40,820 | 37,573 | 3,247 | 8.0% | 98.8% |
| Lowndes | 24,640 | 22,625 | 2,015 | 8.2% | 101.5% |
| Marshall | 13,964 | 12,929 | 1,035 | 7.4% | 92.0% |
| Monroe | 15,464 | 14,118 | 1,346 | 8.7% | 108.1% |
| Montgomery | 3,860 | 3,556 | 304 | 7.9% | 97.8% |
| Noxubee | 3,776 | 3,365 | 411 | 10.9% | 135.1% |
| Oktibbeha | 21,799 | 20,156 | 1,643 | 7.5% | 93.6% |
| Panola | 12,554 | 11,350 | 1,204 | 9.6% | 119.1% |
| Pontotoc | 14,843 | 13,723 | 1,120 | 7.5% | 93.7% |
| Prentiss | 11,038 | 10,290 | 748 | 6.8% | 84.1% |
| Tippah | 9,182 | 8,552 | 630 | 6.9% | 85.2% |
| Tishomingo | 8,246 | 7,714 | 532 | 6.5% | 80.1% |
| Union | 13,932 | 12,960 | 972 | 7.0% | 86.6% |
| Webster | 3,837 | 3,559 | 278 | 7.2% | 90.0% |
| Winston | 7,257 | 6,642 | 615 | 8.5% | 105.2% |
| Yalobusha | 4,841 | 4,469 | 372 | 7.7% | 95.4% |
