| | Population Estimates Base, April 1, 2000 | Population Estimate, July 1, 2009 | Numeric Population Change, April 1, 2000 to July 1, 2009 | Percent Population Change, April 1, 2000 to July 1, 2009 |
|
| United States | 281,424,602 | 307,006,550 | 25,581,948 | 9.1% |
| Appalachian Region | 23,642,949 | 24,993,391 | 1,350,442 | 5.7% |
| North Carolina | 8,046,406 | 9,380,884 | 1,334,478 | 16.6% |
| Appalachian North Carolina | 1,526,110 | 1,662,282 | 136,172 | 8.9% |
|
| County |
| Alexander | 33,603 | 36,777 | 3,174 | 9.4% |
| Alleghany | 10,680 | 10,964 | 284 | 2.7% |
| Ashe | 24,387 | 25,812 | 1,425 | 5.8% |
| Avery | 17,167 | 17,932 | 765 | 4.5% |
| Buncombe | 206,270 | 231,452 | 25,182 | 12.2% |
| Burke | 89,153 | 89,548 | 395 | 0.4% |
| Caldwell | 77,382 | 79,914 | 2,532 | 3.3% |
| Cherokee | 24,296 | 26,307 | 2,011 | 8.3% |
| Clay | 8,775 | 10,333 | 1,558 | 17.8% |
| Davie | 34,835 | 41,420 | 6,585 | 18.9% |
| Forsyth | 306,067 | 359,638 | 53,571 | 17.5% |
| Graham | 7,990 | 8,001 | 11 | 0.1% |
| Haywood | 54,033 | 57,109 | 3,076 | 5.7% |
| Henderson | 89,225 | 103,669 | 14,444 | 16.2% |
| Jackson | 33,124 | 36,891 | 3,767 | 11.4% |
| Macon | 29,808 | 33,233 | 3,425 | 11.5% |
| Madison | 19,643 | 20,442 | 799 | 4.1% |
| McDowell | 42,139 | 43,988 | 1,849 | 4.4% |
| Mitchell | 15,681 | 15,634 | -47 | -0.3% |
| Polk | 18,324 | 19,255 | 931 | 5.1% |
| Rutherford | 62,903 | 63,415 | 512 | 0.8% |
| Stokes | 44,711 | 46,150 | 1,439 | 3.2% |
| Surry | 71,205 | 72,496 | 1,291 | 1.8% |
| Swain | 12,973 | 13,404 | 431 | 3.3% |
| Transylvania | 29,297 | 30,203 | 906 | 3.1% |
| Watauga | 42,703 | 45,479 | 2,776 | 6.5% |
| Wilkes | 65,630 | 66,555 | 925 | 1.4% |
| Yadkin | 36,351 | 37,713 | 1,362 | 3.7% |
| Yancey | 17,755 | 18,548 | 793 | 4.5% |
