| | Civilian Labor Force, 2022 | Persons Employed, 2022 | Persons Unemployed, 2022 | Unemployment Rate, 2022 | Unemployment Rate, Percent of U.S. Average, 2022 |
|
| United States | 164,287,000 | 158,291,000 | 5,996,000 | 3.6% | 100.0% |
| Appalachian Region | 12,135,996 | 11,700,293 | 435,703 | 3.6% | 98.4% |
| South Carolina | 2,393,329 | 2,316,435 | 76,894 | 3.2% | 88.0% |
| Appalachian South Carolina | 637,053 | 617,849 | 19,204 | 3.0% | 82.6% |
|
| County |
| Anderson | 92,055 | 89,311 | 2,744 | 3.0% | 81.7% |
| Cherokee | 24,177 | 23,188 | 989 | 4.1% | 112.1% |
| Greenville | 261,642 | 254,376 | 7,266 | 2.8% | 76.1% |
| Oconee | 34,437 | 33,391 | 1,046 | 3.0% | 83.2% |
| Pickens | 58,341 | 56,548 | 1,793 | 3.1% | 84.2% |
| Spartanburg | 155,135 | 150,296 | 4,839 | 3.1% | 85.5% |
| Union | 11,266 | 10,739 | 527 | 4.7% | 128.2% |
