| | Civilian Labor Force, 2022 | Persons Employed, 2022 | Persons Unemployed, 2022 | Unemployment Rate, 2022 | Unemployment Rate, Percent of U.S. Average, 2022 |
|
| United States | 164,287,000 | 158,291,000 | 5,996,000 | 3.6% | 100.0% |
| Appalachian Region | 12,135,996 | 11,700,293 | 435,703 | 3.6% | 98.4% |
| Virginia | 4,427,292 | 4,304,759 | 122,533 | 2.8% | 75.8% |
| Appalachian Virginia | 336,334 | 325,775 | 10,559 | 3.1% | 86.0% |
|
| County |
| Alleghany (+ Covington city) | 8,881 | 8,578 | 303 | 3.4% | 93.5% |
| Bath | 2,418 | 2,360 | 58 | 2.4% | 65.7% |
| Bland | 2,774 | 2,696 | 78 | 2.8% | 77.0% |
| Botetourt | 17,646 | 17,214 | 432 | 2.4% | 67.1% |
| Buchanan | 6,305 | 6,016 | 289 | 4.6% | 125.6% |
| Carroll (+ Galax city) | 15,685 | 15,157 | 528 | 3.4% | 92.2% |
| Craig | 2,310 | 2,242 | 68 | 2.9% | 80.7% |
| Dickenson | 4,514 | 4,324 | 190 | 4.2% | 115.3% |
| Floyd | 8,460 | 8,256 | 204 | 2.4% | 66.1% |
| Giles | 8,098 | 7,853 | 245 | 3.0% | 82.9% |
| Grayson | 7,974 | 7,769 | 205 | 2.6% | 70.4% |
| Henry (+ Martinsville city) | 29,430 | 28,393 | 1,037 | 3.5% | 96.5% |
| Highland | 1,359 | 1,328 | 31 | 2.3% | 62.5% |
| Lee | 8,194 | 7,893 | 301 | 3.7% | 100.6% |
| Montgomery (+ Radford city) | 60,781 | 59,094 | 1,687 | 2.8% | 76.0% |
| Patrick | 7,163 | 6,914 | 249 | 3.5% | 95.2% |
| Pulaski | 16,602 | 16,104 | 498 | 3.0% | 82.2% |
| Rockbridge (+ Buena Vista city + Lexington city) | 16,188 | 15,709 | 479 | 3.0% | 81.1% |
| Russell | 11,006 | 10,629 | 377 | 3.4% | 93.9% |
| Scott | 9,184 | 8,899 | 285 | 3.1% | 85.0% |
| Smyth | 13,571 | 13,157 | 414 | 3.1% | 83.6% |
| Tazewell | 15,403 | 14,775 | 628 | 4.1% | 111.7% |
| Washington (+ Bristol city) | 33,874 | 32,884 | 990 | 2.9% | 80.1% |
| Wise (+ Norton city) | 14,431 | 13,862 | 569 | 3.9% | 108.0% |
| Wythe | 14,083 | 13,669 | 414 | 2.9% | 80.5% |